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We note that MR-Egger regression has lower statistical power compared to other methods (e.g., IVW) due to its reliance on the Instrument Strength Independent of Direct Effect (InSIDE) assumption and its sensitivity to weak instruments

The loss of insulin sensitivity of hippocampal CA1 pyramidal neurons can subsequently cause long-term Ca 2+ -dependent afterhyperpolarizations (AHPs), which can produce significant cognitive and memory impairment in the short term and throughout life, contributing to depression (122, 123)

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In another study, (Val 8 )GLP-1 might prevent age-related neurodegenerative changes (such as AD) by preventing decline of learning and memory formation, reduction of tau hyperphosphorylation and protection of subcellular structures and morphology of neurons (149)

Two Empower locations have an inspection history that resulted in remedial plans but no formal disciplinary action